Endocrine Abstracts

Internal jugular vein thrombosis (IJVT) is generally related to central venous access devices (CVADs) because of endothelial trauma or inflammation. Other reported causes include neck surgery complication, malignancies, deep neck infections, intravenous drug abuse, ovarian hyperstimulation syndrome and hypercoagulable states.We report the case of a 47-year-old woman presenting with acute neck pain, local swelling and fever. Neck ultrasound with Doppler s...

Pituitary macroadenomas usually present with symptoms due to a local mass effect or to hormone abnormalities. Acromegaly is due an excessive GH production, usually caused by a slow-growing pituitary adenoma. Acromegaly is an insidious disease. An average delay of 7 years is reported between the time of symptoms onset and diagnosis. According to main symptoms, acromegaly is usually diagnosed by internists, ophthalmologists or rheumatologists. It may be suspected by pneumologist...

Introduction: CHH is a genetic syndrome that combines reproductive and brain abnormalities. The brain phenotype has been incompletely characterized. We aimed to study neuroradiological and genetic features in this first Belgian series of patients with CHH.Methods: A series of 56 adult patients (48 males, 8 females) presenting with CHH was investigated for a panel of 16 genes related to hypogonadotropic hypogonadism by next generation sequencing on a MiSe...